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Chromosomal Aberration: Structural and Numerical

What is Chromosomal Aberration? Any type of change in the structure and number of chromosomes due to certain irregularities during cell division is known as chromosomal aberration. Broadly such aberrations are divided into two major groups. Structural aberration Numerical aberration Again, structural aberrations are of 4 types. Such as: Deletion …

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Solenoid Model: The Second Level of Packing

In the nucleosome model of chromosome, we have discussed about the fundamental organizational unit of chromosome termed as nucleosome. That article gave us a simplistic idea about how the repeated nucleosomes are arranged. The figure in the right hand side clarifies that the nucleosome model provides us with the insight …

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Nucleosome Model of Chromosomes

Let’s kick off this discussion with a simple calculation about the length of DNA in a single diploid human cell. We know according to Watson and Crick model of double helix DNA, each two base pairs has a distance of 3.4 A. There are approximately 6.4 billion base pairs (bp) …

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