Linkage and recombination

Gene mapping

The diagrammatic representation of location and arrangement of genes and relative distance between  linked gene of a chromosome is called linkage map or genetic map.

Unit of genetic map is Morgan or Centimorgan.

History

Test cross

Gene map distance

If the percentage of crossing over between two linked gene is 1%, then the map distance between linked gene will be 1 M.

The probability of crossing over between two genes is directly proportional to distance between them.

When two genes are nearer, the probability of crossing over between them is limited.

The probability of making a random cut between the two knots/genes is proportional to the distance between them.

Every cut separates A from E whereas 5/100 cut only separates C from D.

Uses of gene mapping-

  • Useful to determine the location, arrangement and linkage of genes in a chromosome.
  • Useful to predict the result of dihybrid and trihybrid crosses.

Two point test cross in Drosophilla

Map distance

What is 3 point cross

3 point cross in Drosophila



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About Shakila Mahbuba

Currently studying in 2nd year(BS Hon's) in the Department of Botany, University of Dhaka. I contain a little amount of knowledge of the vast Bioscience and Plant Science world. I'm running out of thirst for more knowledge related to this branch and have tried to write a little bit here. Please Forgive my mistakes and let me know about those. Email: shakilamahbuba27@gmail.com Minimum monthly resolution - Publish (1), Revise (2), Share (3)

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