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Transposable Genetic Elements

Transposons were first discovered in corn (maize) during the 1940s and ’50s by American scientist Barbara McClintock, whose work won her the Nobel Prize for Physiology or Medicine in 1983. The colourful pattern on maize ears have an important scientific significance. Modern research have shown that the stripes and spots …

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DNA Replication in Eukaryotes: Linear Replication

DNA replication in eukaryotes is a complex and unique process involving many enzymes and thousands of ORI at a single time. Unlike the prokaryotic DNA, it involves a linear mode of replication. Why does linear DNA replication involve  multiple origins at a time? The large linear chromosomes in eukaryotic cell …

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Replication in Circular DNA: Theta Model

Following Meselson and Stahl’s work, investigators confirmed that other organisms also use semiconservative replication. There are, however, several different ways that semiconservative replication can take place, differing principally in the nature of the template DNA—whether it is linear or circular—and in the number of replication forks. Replicon and Origin of …

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